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Recruiting

Molecular Analysis of Oncogenes and Resistance Mechanisms in Lung Cancer

About this study

The mechanisms of sensitivity and resistance to oncogene-targeted therapy can be determined from tumor tissue or tumor cell lines derived from available archival samples and/or from standard-of-care re-biopsy upon suspected tumor progression.

Condition
Lung Neoplasms
Sponsor
University of Colorado, Denver

Who can join

Age
18 to 85 years
Sex
All sexes
Healthy volunteers
Not accepted

Inclusion 7

  • Minimum age: 18 years
  • Maximum age: 85 years
  • Study condition: Lung Neoplasms
  • Patients undergoing investigation or treatment for thoracic cancers with oncogene-targeted therapies
  • Aged 18 years or older
  • Either a) have suspected tumor progression or other condition that dictates a standard-of-care palliative, therapeutic, or diagnostic intervention including but not limited to procedures such as bronchoscopic biopsy, computed tomography (CT) or ultra-sound (US)-guided biopsy, thoracentesis, video assisted thoracoscopic (VATS) pleurodesis, lobectomy, adrenalectomy or pleural catheter placement, providing tumor specimen appropriate molecular analysis or b) have previously had biopsy/surgical intervention with tumor tissue at University of Colorado or an outside institution available for medullar analysis.
  • Patients must have the ability to understand and willingness to sign an informed consent document.

Where

1 site, 1 recruiting

University of Colorado Cancer Center

Aurora, Colorado, United States

Recruiting

Contact

Potential match only. Final eligibility is determined by the study team.