Predictive Factors of Autonomy Loss in Real-life Cohort
About this study
The Alzheimer's disease or related disorders (ADRD) are among the most disabling diseases because of their main features such as cognitive impairment, loss of functional autonomy and behavioural disorders. In absence of current curative treatment, the identification of the predictive risk factors of progression of the disease, evaluated through its main symptoms, represents a major stake of public health. The Investigators aim at developing a regional database, which includes the patient medical records on a prospective basis, in collaboration with the medical and administrative staff and with the University hospital computer science departments. The main objective is to study the predictive factors associated with change in functional autonomy level, measured every 6 to 12 months in centres across Region Auvergne Rhone-Alpes in France. The real-life study population will consist in about 5400 patients with ADRD. The inclusion period will be of 3 years, the length of follow-up of each patient will be of 10 years max for a total study length of 13 years.
- Condition
- Memory Disorders
- Tested
- no intervention
- Sponsor
- Hospices Civils de Lyon
Who can join
- Age
- 18 years and older
- Sex
- All sexes
- Healthy volunteers
- Not accepted
Inclusion 5
- Minimum age: 18 years
- Study condition: Memory Disorders
- Patients aged 18 years and older, undergoing a medical visit in a memory center or neuro-cognition service
- Patients living at home or in housing
- Patients with memory impairment, at all stage of the disease
Exclusion 3
- Patients in institution
- Patients under legal protection
- Patients with a hearing or visual impairment, which prevents carrying out examinations
Where
5 sites, 5 recruiting
Hôpital Dugoujon
Caluire-et-Cuire, France
Centre Hospitalier Lyon Sud
Lyon, France
Service de neuro-cognition et neuro-ophtalmologie du Groupement Hospitalier Est
Lyon, France
CHU Saint-Etienne
Saint-Etienne, France
Centre Mémoire de Ressources et de Recherche de Lyon
Villeurbanne, France
Contact
-
Pierre Krolak-Salmon, PhD
04 72 43 20 50 pierre.krolak-salmon@chu-lyon.fr
Potential match only. Final eligibility is determined by the study team.