Registry of Subjects at Risk of Pancreatic Cancer
About this study
IRFARPC is a multicenter national registry designed to study the diagnosis and predisposing factors of subjects with an inherited increased risk for pancreatic cancer.
- Condition
- Familial Pancreatic Cancer, BRCA1 Mutation, BRCA2 Mutation, Lynch Syndrome, FAMMM - Familial Atypical Mole Malignant Melanoma Syndrome, Hereditary Pancreatitis, Peutz-Jeghers Syndrome
- Tested
- MRCP, Endoultrasonography
- Sponsor
- Associazione Italiana per lo Studio del Pancreas
Who can join
- Age
- 18 to 80 years
- Sex
- All sexes
- Healthy volunteers
- Not stated
Inclusion 12
- Minimum age: 18 years
- Maximum age: 80 years
- Study condition: Familial Pancreatic Cancer, BRCA1 Mutation, BRCA2 Mutation, Lynch Syndrome, FAMMM - Familial Atypical Mole Malignant Melanoma Syndrome, Hereditary Pancreatitis, Peutz-Jeghers Syndrome
- individuals with at least two relatives suffering from pancreatic cancer, with at least 1 first-degree and until the third-degree
- subjects with known genetic mutation of BRCA2, BRCA1, p16, PALB2 with at least 1 first- or 2nd-degree relative suffering from pancreatic cancer
- subjects suffering from FAMMM Syndrome
- subjects suffering from Peutz-Jeghers Syndrome
- subjects suffering from PRSS-1- or CFTR- or SPINK-1- related pancreatitis
- subjects suffering from Lynch syndrome with at least 1 first- or 2nd-degree relative suffering from pancreatic cancer
- 45 years or 10 years younger than the youngest index case of pancreatic cancer in the family for familial cases
- 40 years or 5 years younger than the youngest index case of pancreatic cancer for subjects suffering from hereditary/genetic pancreatitis, Lynch syndrome, or carrying a known BRCA 1/2, PALB2, p16 genetic mutation with familiarity for pancreatic cancer
- 30 years for subjects suffering from FAMMM, Peutz-Jeghers syndrome
Exclusion 1
- \- pregnancy
Where
4 sites, 4 recruiting
San Raffele Vita Salute University Hospital
Milan, Italy
Ospedale Pederzoli
Peschiera del Garda, Verona, Italy
Istituto Clinico Humanitas
Rozzano, Milan, Italy
Chirurgia Generale e del Pancreas
Verona, Italy
Contact
-
Salvatore Paiella, MD, PhD
00390458126009 salvatore.paiella@univr.it
-
Silvia Carrara, MD
+ 39 02 82247288 silvia.carrara@humanitas.it
Potential match only. Final eligibility is determined by the study team.