Recruiting
Active Surveillance for Low Risk Prostate Cancer
About this study
An active surveillance protocol for patients diagnosed low-risk prostate cancer will be held. We plan to use PSA (prostate-specific antigen) testing, DRE (digital rectal examination), TRUS (transrectal ultrasound), MRI (magnetic resonance imaging) and follow-up biopsies to monitor patients and detect cancer progression in time.
- Condition
- Prostate Cancer, Prostate Adenocarcinoma
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Who can join
- Age
- 50 to 75 years
- Sex
- Male only
- Healthy volunteers
- Not accepted
Inclusion 8
- Minimum age: 50 years
- Maximum age: 75 years
- Eligible sex: Male
- Study condition: Prostate Cancer, Prostate Adenocarcinoma
- prostate adenocarcinoma verified by at least 12 core biopsy
- patient must understand the sense of research, agree to participate and sign a form of agreement
- low oncological risk according to EAU (European Association of Urology) Guidelines: stage T1-T2a, PSA\<10 ng/ml, ISUP (International Society of Urological Pathologists score)=1 (Gleason score 3+3=6)
- not more than 33% cores with adenocarcinoma
Exclusion 6
- previous treatment of prostate cancer
- other prostatic malignant neoplasms
- other oncological diseases
- treatment with 5-alfa-reductase inhibitors
- patient's refuse to continue study
- patient's desire to begin treatment
Where
1 site, 1 recruiting
Institute for Urology and Reproductive Health, Sechenov University.
Moscow, Russia
Potential match only. Final eligibility is determined by the study team.