Analysis of the Immunobiology of Acute Myeloid Leukemia Relapses After Allogeneic Hematopoietic Stem Cell Transplant (HSCT) for the Generation of Guidelines and Personalized Therapeutic Pathways
About this study
This is a retrospective and prospective non-interventional multicenter observational study. Neither diagnostic approaches nor experimental drugs/procedure will be applied and the samples will take place at the same time as the samples will be taken during routinary clinical practice. The aim of this study is to analyze the immunobiology of Acute Myeloid Leukemia (AML) relapses after allogeneic HSCT for the generation of guidelines and personalized therapeutic pathways.
- Condition
- Acute Myeloid Leukemia, in Relapse
- Tested
- Observations on Relapsed AML Allogeneic Transplanted patients
- Sponsor
- Ciceri Fabio
Who can join
- Age
- 18 years and older
- Sex
- All sexes
- Healthy volunteers
- Not accepted
Inclusion 5
- Minimum age: 18 years
- Study condition: Acute Myeloid Leukemia, in Relapse
- Adult patients with Acute Myeloid Leukemia, who relapse after allogeneic transplantation from either family or unrelated donors, regardless of the cellular source of the transplant (bone marrow, mobilized peripheral stem cells or cord blood), who have signed the informed consent of the study;
- For the coordinating center, all patients who have previously signed informed consent to the "Hematological Neoplasms Biobank" and for which samples, stored in the Biobank are available.
- For the other centers, all patients who have previously signed an informed consent, aimed at the prior authorization for the storage of samples in the biobank of the aforementioned center, according to centers own practice, and for which samples, stored in a Biobank, are available.
Exclusion 1
- Participation in clinical protocols that expressly exclude the possibility of participating in other studies.
Where
1 site, 1 recruiting
IRCCS Ospedale San Raffaele
Milan, Milano, Italy
Contact
-
Fabio Ciceri, MD
+39 02-2643-3093 ciceri.clinicaltrials@hsr.it
-
Stefania Trinca
+39 02-2643-4289 regolatorio.scp@hsr.it
Potential match only. Final eligibility is determined by the study team.