Music Therapy for Patients With Alzheimer's Disease
About this study
This study is designed to assess the feasibility that individualized reminiscence-based virtual music therapy sessions can enhance autobiographical memory, mood, and cognition in patients with mild cognitive impairment (MCI) or mild dementia due to Alzheimer's Disease (AD). 60 patients with MCI or mild dementia due to AD will receive two 30 minutes reminiscence-targeted virtual music therapy interventions per week for 8 weeks (a total of 16 sessions). Participants' (or supported by the study partner) self-reported and measurable outcomes including cognitive, anxiety, quality of life, and autobiographical memory will be assessed before and after the 8-week course of treatment. Blood-oxygenation level-dependent (BOLD) in functional magnetic resonance imaging (fMRI) will also be also measured before and after the 8-week course of treatment.
- Condition
- Mild Cognitive Impairment, Alzheimer Disease
- Tested
- Virtual Music Therapy
- Sponsor
- Johns Hopkins University
Who can join
- Age
- 18 to 89 years
- Sex
- All sexes
- Healthy volunteers
- Not accepted
Inclusion 5
- Minimum age: 18 years
- Maximum age: 89 years
- Study condition: Mild Cognitive Impairment, Alzheimer Disease
- Age 18-89
- Mild Cognitive Impairment (MoCA score: 18-25) or Early AD (MoCA score: 17-24)
Exclusion 4
- Head trauma, traumatic brain injury, or concussion with loss of consciousness for \>2 minutes
- Claustrophobia incompatible with MRI scanning
- Medical device incompatible with MRI scanning (e.g. cardiac pacemaker, implanted cardiac defibrillator, aneurysm brain clip, inner ear implant)
- Prior history as a metal worker and/or certain metallic objects in the body
Where
1 site, 1 recruiting
Johns Hopkins School of Medicine
Baltimore, Maryland, United States
Contact
-
Alexander Pantelyat, MD
4105023290 apantel1@jhmi.edu
-
Kyurim Kang, PhD
4437422223 kkang19@jhmi.edu
Potential match only. Final eligibility is determined by the study team.