Tranexamic Acid During Colonic Endoscopic Resection Procedures
About this study
Colonoscopy with polypectomy reduces the incidence and mortality associated with colon cancer. However, polypectomy is associated with adverse events such as bleeding. Tranexamic acid (TXA) is a synthetic derivative of lysine that exerts antifibrinolytic effects and may prevent bleeding. The investigators aim to evaluate the effect of local TXA on preventing intraprocedural and postprocedural bleeding in patients undergoing endoscopic mucosal resection (EMR) of large colon polyps.
- Condition
- Colon Neoplasm
- Tested
- Tranexamic acid, Standard
- Sponsor
- Assaf-Harofeh Medical Center
Who can join
- Age
- 18 years and older
- Sex
- All sexes
- Healthy volunteers
- Not accepted
Inclusion 4
- Minimum age: 18 years
- Study condition: Colon Neoplasm
- Patients referred for endoscopic resection of non-neoplastic and neoplastic lesions in the colon presenting to our tertiary academic center.
- Age \> 18 years
Exclusion 3
- patients with histories of allergic reactions to TXA
- history of seizures
- pregnancy
Where
1 site, 1 recruiting
Shamir Medical Center
Be’er Ya‘aqov, Israel
Contact
-
Anton Bermont, MD
+972526944145 bermont@doctor.com
-
Sergei Vosko, MD
Potential match only. Final eligibility is determined by the study team.