Recruiting
Phase 4
Choline Fenofibrate and Carotid Atherosclerosis in Patients With Type 2 Diabetes and Combined Dyslipidemia
About this study
This is a randomized controlled study to assess the effect of choline fenofibrate compared with policosanol in Korean T2DM patients with asymptomatic atherosclerosis.
- Condition
- Dyslipidemia, Atherosclerosis, Diabetes Mellitus, Type 2
- Tested
- Choline fenofibrate, Policosanol
- Sponsor
- Seoul National University Bundang Hospital
Who can join
- Age
- 20 years and older
- Sex
- All sexes
- Healthy volunteers
- Not accepted
Inclusion 7
- Minimum age: 20 years
- Study condition: Dyslipidemia, Atherosclerosis, Diabetes Mellitus, Type 2
- Type 2 diabetes under treatment with HbA1c 6.0-10.0% at screening visit
- Male or female of 20 years or over
- Mixed dyslipidemia: triglyceride 200\~499 mg/dL, HDL-cholesterol male ≤45 mg/dL or female ≤50 mg/dL
- Identified carotid artery plaque: carotid intima-media thickness (cIMT) ≥ 1.0 mm
- Creatinine ≤1.8 mg/dL
Exclusion 7
- Dyslipidemia which requires other therapy: triglyceride ≥500 mg/dL or LDL-cholesterol ≥190 mg/dL
- Uncontrolled hypertension
- Severe renal dysfunction
- GOT/GPT \>120/120 or chronic liver disease
- Pregnant or childbearing woman who does not have enough contraception
- Changes of medication related to chronic diseases (diabetes, hypertension, dyslipidemia, etc.) within 3 months
- Other antiplatlet medication such as cilostazol, clopidogrel (except aspirin)
Where
1 site, 1 recruiting
SNUBH
Seongnam-si, Gyeonggi-do, South Korea
Contact
-
Soo Lim
+82-31-787-7035 limsoo@snu.ac.kr
-
Minji Sohn
Potential match only. Final eligibility is determined by the study team.