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About this study

This project will assess how depression, preclinical AD, and antidepressants affect driving behavior in cognitively normal older adults (65 years).

Condition
Depression, Drive
Tested
F 18 AV-1451 (Flortaucipir), [11C]-Pittsburgh Compound B ([11C]PiB)
Sponsor
Washington University School of Medicine

Who can join

Age
65 years and older
Sex
All sexes
Healthy volunteers
Not stated

Inclusion 8

  • Minimum age: 65 years
  • Study condition: Depression, Drive
  • Drive on average at least once per week
  • Has a valid driver's license
  • Willing to complete blood draw
  • Willing to complete either lumbar puncture or PET imaging
  • 65 years or older
  • Speaks English

Exclusion 3

  • Not willing to complete blood draw and/or one other biomarker
  • Less than 65 years of age
  • Does not drive a vehicle/ is no longer actively driving

Where

1 site, 1 recruiting

Washington University School of Medicine

St Louis, Missouri, United States

Recruiting

Contact

Potential match only. Final eligibility is determined by the study team.