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Pre- and Post-operative TEG Indices in Patients With or Without Adenocarcinoma Undergoing Surgical Resection

About this study

The investigators hypothesize that abnormalities in thromboelastography (TEG) parameters in patients with liver, pancreas, biliary, esophageal, colorectal, and lung adenocarcinoma can serve as biomarkers for oncologic disease burden, cancer recurrence and overall survival as well as thrombotic and hemorrhagic post-operative complications. The investigators further hypothesize that there is histologic pathology correlates to pre-operative TEG abnormalities, and that it identifies patients with virulent tumor biology.

Condition
Liver Cancer, Esophageal Cancer, Colorectal Cancer, Lung Adenocarcinoma, Control, Pancreas Cancer, Biliary Cancer
Tested
TEG indices
Sponsor
University of Colorado, Denver

Who can join

Age
18 to 99 years
Sex
All sexes
Healthy volunteers
Accepted

Inclusion 5

  • Minimum age: 18 years
  • Maximum age: 99 years
  • Study condition: Liver Cancer, Esophageal Cancer, Colorectal Cancer, Lung Adenocarcinoma, Control, Pancreas Cancer, Biliary Cancer
  • new diagnosis by the providing physician of hepatopancreaticobiliary, esophageal, colorectal, lung adenocarcinoma, or liver metastasis of any origin will be eligible for enrollment in the study
  • 18 Years and older

Exclusion 5

  • Under 18 years old
  • prisoners
  • unable to provide informed consent
  • pregnant women
  • and those undergoing emergent or urgent operative intervention at the time of diagnosis

Where

2 sites, 2 recruiting

University of Colorado Denver

Aurora, Colorado, United States

Recruiting

UCHealth Highlands Ranch Hospital

Highlands Ranch, Colorado, United States

Recruiting

Contact

Potential match only. Final eligibility is determined by the study team.