Anxiety Sensitivity Treatment to Reduce Anxiety in Alzheimer's
About this study
The goal of this clinical trial is to test the effectiveness of a computerized anxiety sensitivity treatment (CAST) compared to a health education control (HEC) in older adults with mild cognitive impairment (MCI) or mild Alzheimer's Disease and related dementias (ADRD) and their care partners. The main questions it aims to answer are: 1. Efficacy of CAST in reducing anxiety and related symptoms among those with MCI/mild ADRD 2. Efficacy of CAST in reducing care partner burden among care partners of people living with MCI/mild ADRD 3. Explore treatment mechanisms using a multi-modal assessment battery of anxiety sensitivity and anxiety Participants will complete six in-person visits including a baseline assessment, two intervention sessions, and three follow-up assessments at 1, 3, and 6-months posttreatment. Participants will also complete three weeks of ecological momentary assessments (EMAs) for one week prior to intervention, one week between intervention sessions, and one week after intervention. If there is a comparison group: Researchers will compare CAST to HEC to see if CAST reduces anxiety and related symptoms in older adults with MCI/mild ADRD and care partner burden to a greater degree than HEC.
- Condition
- Anxiety, Mild Cognitive Impairment, Alzheimer Disease, Dementia
- Tested
- Computerized Anxiety Sensitivity Treatment, Health Education Control
- Sponsor
- Florida State University
Who can join
- Age
- 60 years and older
- Sex
- All sexes
- Healthy volunteers
- Not accepted
Inclusion 14
- Minimum age: 60 years
- Study condition: Anxiety, Mild Cognitive Impairment, Alzheimer Disease, Dementia
- Patient age 60+
- Care partner 18+
- Has care partner who will participate ("someone you have a reciprocal relationship with who provides you with emotional or physical support and helps with decision-making. This could be a spouse or significant other, relative, or close friend whom you spend a significant amount of time with.")
- Has smartphone or access to Wi-Fi
- EITHER
- Score of 20 or above on the PROMIS-Anxiety short form (patient only) OR
- Score of 5 or above on SSASI (patient only) OR
- Score of 31 or above on NIH Toolbox Perceived Stress Scale score (patient only)
- AND EITHER
- Participant MoCA score is between 17 to 26
- Participant Memory Complaint Scale score 3 or greater
- Care partner quick dementia rating scale score between 2 to 12.5
Exclusion 5
- PATIENT
- Issues with seeing or hearing that would prevent reading or listening to computer presentations
- Medical conditions that would preclude participation in study
- Severe mental illness (e.g., schizophrenia, unmedicated bipolar disorder)
- CARE PARTNER
Where
3 sites, 3 recruiting
Ohio University
Athens, Ohio, United States
The Ohio State University
Columbus, Ohio, United States
Anxiety and Behavioral Health Clinic
Tallahassee, Florida, United States
Contact
-
Norman B Schmidt, Ph.D.
8506451766 schmidt@psy.fsu.edu
-
Frederick T Schubert, B.A.
8045439845 schubert@psy.fsu.edu
Potential match only. Final eligibility is determined by the study team.