Primary Cardiac Lymphoma: Italian Multicenter Experience
About this study
The rationale of this study is to provide an overview on PCL (Primary Cardiac Lymphoma) in Italy, trying to shed light on unknown aspects of the disease and on unanswered questions about its management that could be helpful in clinical practice.
- Condition
- Primary Cardiac Lymphoma
- Sponsor
- Fondazione Italiana Linfomi - ETS
Who can join
- Age
- 18 years and older
- Sex
- All sexes
- Healthy volunteers
- Not stated
Inclusion 8
- Minimum age: 18 years
- Study condition: Primary Cardiac Lymphoma
- Diagnosis of PCL (any histotype) defined as an extranodal lymphoma involving only the heart with possible involvement of the pericardium.
- Age ≥18 years.
- Diagnosis histologically confirmed. Cytofluorimetry analysis of pericardial fluid showing phenotypic features consistent with a primary cardiac lymphoma is permitted if a biopsy sample is not feasible/available for diagnosis; monoclonality is not accepted as a surrogate for diagnosis.
- Date of diagnosis: from 1st January 2000 to 31st December 2020.
- Only patients treated in first-line with chemoimmunotherapy regimens including an anti-CD20 monoclonal antibody are eligible for the study.
- Signed written informed consent (in case of unreachable subject please see chapter 11.2)
Exclusion 3
- Secondary cardiac involvement from lymphoma; primary mediastinal lymphoma with pericardial infiltration or other lymphomas with involvement of the pericardium/the heart by contiguity and primary effusion lymphoma are not included in this study.
- Patients treated with chemotherapy regimens that did not include an anti-CD20 monoclonal antibody as first-line therapy.
- Refuse to sign a written informed consent
Where
13 sites, 13 recruiting
Azienda Ospedaliera Papa Giovanni XXIII - Ematologia
Bergamo, Bergamo, Italy
ASST Spedali Civili di Brescia - Ematologia
Brescia, Brescia, Italy
Azienda Ospedaliero-Universitaria di Ferrara - Arcispedale Sant'Anna - Ematologia e fisiopatologia della coagulazione
Ferrara, Ferrara, Italy
Istituto Scientifico San Raffaele - Unitа Linfomi - Dipartimento Oncoematologia
Milan, Milano, Italy
Fondazione IRCCS Istituto Nazionale dei Tumori di Milano - Ematologia
Milan, Milano, Italy
ASST Grande Ospedale Metropolitano Niguarda - SC Ematologia
Milan, Milano, Italy
and 7 more sites on ClinicalTrials.gov
Contact
-
Giorgio Priolo
0131.033175 gpriolo@filinf.it
-
Samantha Deianira Dattoli
0599769914 sdattoli@filinf.it
Potential match only. Final eligibility is determined by the study team.