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Recruiting

Exploring Cancer Evolution, Prognostic and Predictive Biomarkers in EGFR-mutant NSCLC

About this study

To investigate genomic architecture, cancer evolution and their relationship with clinical outcomes in EGFR-mutant NSCLC.

Condition
Non-small Cell Lung Cancer
Sponsor
Sun Yat-sen University

Who can join

Age
18 years and older
Sex
All sexes
Healthy volunteers
Not accepted

Inclusion 8

  • Minimum age: 18 years
  • Study condition: Non-small Cell Lung Cancer
  • Aged 18 years or older
  • Histologically or cytologically confirmed non-small-cell lung cancer
  • ECOG PS=0-2
  • EGFR mutations confirmed by tissue or peripheral blood
  • Can provide tumor tissue samples (fresh or archived)
  • The subject should have good compliance, who would participate in the research voluntarily, and sign the informed consent

Exclusion 4

  • History of other malignancies within 5 years (excluding basal cell carcinoma of the skin or other carcinoma in situ that has been resected).
  • Unable to provide sufficient tumor tissue for analysis.
  • Subjects with active, unstable systemic diseases, such as active infection, uncontrolled hypertension, heart failure (NYHA class \>= II), unstable angina pectoris, acute coronary syndrome, severe arrythmia, severe liver, kidney or metabolic diseases, HIV infection.
  • Subjects who are deemed unable to comply with the study requirements or complete the study.

Where

1 site, 1 recruiting

Sun Yat-sen University Cancer Center

Guanzhou, China

Recruiting

Contact

Potential match only. Final eligibility is determined by the study team.