Fetal Cell Receptors Repertoire
About this study
The purpose of this study is to describe the transcriptomic profile of foetal cells in post-partum and more specifically to determine which chemokine receptors are overexpressed in foetal cells in post-partum women with wounds To do so, the investigators will isolate foetal cells from the peripheral blood of healthy controls post partum women as well as from post partum women with skin ulcers and then perform RNA sequencing.
- Condition
- Venous Ulcer, Sickle Cell Ulcer, Diabetic Ulcer, Post-partum Women, Mixed Ulcer
- Tested
- Saliva sampling, Blood sampling, Interviews, Clinical examination
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Who can join
- Age
- Not specified
- Sex
- All sexes
- Healthy volunteers
- Accepted
Inclusion 14
- Study condition: Venous Ulcer, Sickle Cell Ulcer, Diabetic Ulcer, Post-partum Women, Mixed Ulcer
- Common criteria :
- Adult women,
- Post-partum: having been pregnant for any length of time,
- Having signed a free and informed consent form,
- Primiparous or multiparous,
- Affiliated to a health insurance
- Patients :
- \- Patients with a venous, diabetic or sickle cell ulcer, or mixed ulcer
- Control group patients :
- Volunteers,
- Age-matched,
- Without skin ulcers.
- There are no specific criteria for children.
Exclusion 5
- Minors (for patients)
- Under court protection, curatorship, guardianship (for patients)
- Immunocompromised patients for any reason whatsoever
- Refusal of consent
- Refusal of blood and/or saliva samples for themselves or a member of their family
Where
1 site, 1 recruiting
Dermatology unit - Cochin Hospital - APHP
Paris, Île-de-France Region, France
Contact
-
Sélim ARACTINGI, MD, PHD
00 33 1 58 41 18 13 selim.aractingi@aphp.fr
-
Marie Benhammani-Godard
00 33 1 58 41 11 90 marie.godard@aphp.fr
Potential match only. Final eligibility is determined by the study team.