Cognitive Leisure and Preclinical Alzheimer's Disease: Exploring Neural Mechanisms
About this study
The goal of this clinical trial is aims to: 1. Translate and culturally adapt the Cognitive Leisure Activity Scale (CLAS) into Chinese and Conduct reliability and validity tests for the Chinese version of CLAS. 2. Investigate the correlation between cognitive leisure activity levels and cognitive function in the preclinical stage of Alzheimer's Disease (AD). 3. Clarify the regulatory mechanisms of cognitive leisure activity levels on the neural circuits of patients in the preclinical stage of AD.
- Condition
- Cognitive Dysfunction
- Tested
- Relationship of the cognitive leisure activity levels, cognitive function, and MRI characteristics.
- Sponsor
- Yuanjiao Yan
Who can join
- Age
- 60 years and older
- Sex
- All sexes
- Healthy volunteers
- Accepted
Inclusion 5
- Minimum age: 60 years
- Study condition: Cognitive Dysfunction
- Clinical diagnosis of Mild Cognitive Impairment (MCI) and Subjective Cognitive Decline (SCD)
- Age ≥ 60 years
- Capable of normal communication in Mandarin，possesses a certain level of comprehension and judgment.
Exclusion 2
- Individuals with severe hearing or language impairments, or with severe physical illnesses that are unable to cooperate with the survey
- Individuals with pacemakers, metallic implants, cochlear implants, claustrophobia, and other contraindications for MRI examination.
Where
1 site, 1 recruiting
Fujian Provincial Hospital
Fuzhou, Fujian, China
Contact
-
Fayang Lian, MD
0591-87557768 fjslkyk@163.com
Potential match only. Final eligibility is determined by the study team.