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BostonGene and Exigent Genomic INsight Study

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About this study

The BEGIN Study by BostonGene and Exigent Genomic INsight evaluates the efficacy of comprehensive molecular testing in advanced cancer patients. Using the BostonGene Tumor Portrait test, the study aims to identify actionable findings, assess feasibility, and determine patient enrollment in clinical trials. Four cohorts of 100 patients each will be studied over two years, focusing on treatment decisions and patient outcomes. This study seeks to demonstrate the clinical utility of genomic testing in guiding therapy for advanced cancer patients in community settings.

Condition
Breast Cancer, Non-small Cell Lung Cancer, Melanoma, Sarcoma
Sponsor
BostonGene

Who can join

Age
18 years and older
Sex
All sexes
Healthy volunteers
Not accepted

Inclusion 8

  • Minimum age: 18 years
  • Study condition: Breast Cancer, Non-small Cell Lung Cancer, Melanoma, Sarcoma
  • Patients must have a confirmed malignancy of:
  • Locally recurrent, unresectable, or metastatic breast cancer or; Unresectable stage III or metastatic non-small cell lung cancer or; Unresectable or metastatic melanoma or; Locally advanced or metastatic l sarcoma.
  • Life expectancy \> 3 months as per the treating physician
  • Willingness to provide informed consent
  • Living in the United States at time of enrollment
  • Agree to participate in genomic and molecular profiling

Exclusion 1

  • not meeting the inclusion criteria

Where

7 sites, 7 recruiting

New Mexico Cancer Center

Albuquerque, New Mexico, United States

Recruiting

Fort Wayne Medical Oncology and Hematology

Fort Wayne, Indiana, United States

Recruiting

Oncology Consultants

Houston, Texas, United States

Recruiting

Northwest Medical Specialities

Puyallup, Washington, United States

Recruiting

Highlands Oncology Group

Rogers, Arkansas, United States

Recruiting

Stockton Hematology Oncology Medical Group

Stockton, California, United States

Recruiting

and 1 more site on ClinicalTrials.gov

Contact

Potential match only. Final eligibility is determined by the study team.