Effect of Lidocaine on Postoperative Pain and Long-term Survival in Elderly Patients Undergoing Colorectal Surgery
About this study
This study is a further observation and follow-up of the patients enrolled in the registration number NCT05920980 to further evaluate the effect of long-term infusion of lidocaine on postoperative chronic pain, long-term quality of life and survival rate in patients undergoing colorectal cancer surgery.
- Condition
- Colorectal Cancer
- Tested
- lidocaine, Placebo
- Sponsor
- West China Hospital
Who can join
- Age
- 60 years and older
- Sex
- All sexes
- Healthy volunteers
- Not accepted
Inclusion 6
- Minimum age: 60 years
- Study condition: Colorectal Cancer
- Participants were at least 60 years old;
- American Society of Anesthesiologists (ASA) physical status I to III;
- Body-mass index of 18-30 kg/m2;
- Scheduled for elective colorectal surgery.
Exclusion 6
- Metastases occurring in other distant organs;
- Severe hepatic insufficiency (aspartate aminotransferase or alaninetransaminase or bilirubin \>2.5 times the upper limit of normal);
- Renal impairment (creatinine clearance \<60 mL/min);
- Cardiac rhythm disorders or systolic heart failure (second-and thirddegree heart block, ejection fraction \<50%);
- Allergies to any of the trial drugs; chronic opioid use;
- Inability to comprehend numeric rating scale.
Where
1 site, 1 recruiting
China
Sichuan, China
Contact
-
Chunling Jiang, PhD
18980601096 jiang_chunling@yahoo.com
-
Qian Li, PhD
18980601096 jiang_chunling@yahoo.com
Potential match only. Final eligibility is determined by the study team.