Multimodal Assesment of Alzheimer Patients
About this study
The goal of this study is to learn more about the changes in the brains of patients with cognitive impairment (MCI) and Alzheimer's Disease (AD). The main questions the study aims to answer are: 1. What findings can be used to earlier detect patients that will develop Alzheimers? 2. Which differences are seen between healthy and cognitively impaired patients? 3. Which differences are seen between patients with Alzheimers disease? Participants will undergo: * Cognitive tests * Magnetic resonance imaging (MRI) * Electroencephalography (EEG) * Blood sample collection * Fecal sample collection * A randomized group will undergo polysomnography analysis.
- Condition
- Mild Cognitive Impairment, Alzheimer Disease, Late Onset, Cognitive Impairment, Dementia
- Tested
- MRI Scanning, 64-channel EEG, Polysomnography, Blood samples, Fecal samples, Cognitive tests
- Sponsor
- Norwegian University of Science and Technology
Who can join
- Age
- 65 years and older
- Sex
- All sexes
- Healthy volunteers
- Accepted
Inclusion 4
- Minimum age: 65 years
- Study condition: Mild Cognitive Impairment, Alzheimer Disease, Late Onset, Cognitive Impairment, Dementia
- MCI and AD according to relevant ICD-criterias.
- Control cohort is age and gender matched with other cohorts.
Exclusion 7
- Uneligibility for any of the planned neuroimagery devices (MRI, EEG)
- AD diagnosis before the age of 65 (Early-onset AD).
- Brain tumor
- Traumtic head injury
- Earlier neurosurgery
- Other neyrodegenerative diseases (i.e Parkinson and ALS)
- Diseases related to inflammation and auto-immunity (i.e MS)
Where
1 site, 1 recruiting
Norwegian University of Sciene and Technology / Norges teknisk-naturvitenskapelige universitet (NTNU)
Trondheim, Trønderlag, Norway
Contact
-
Axel Sandvig, Prof., MD, PhD
72 57 56 20 axel.sandvig@ntnu.no
Potential match only. Final eligibility is determined by the study team.