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Pressure Pain Tolerance in Relation to Balance and Strength in Children

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About this study

Sickle cell disease (SCD) is the most frequent life-threatening genetic hemoglobinopathy in the world and occurs due to the synthesis of abnormal hemoglobin S (HbS).Cells with sickle cell hemoglobin are stiff and sticky. When they lose their oxygen, they form into the shape of a sickle or crescent. This can cause pain and tissue damage. Significant decrease in exercise capacity was seen in sickle cell anemic children. In the absence of a guidelines that can guide the prescription of exercise in SCD children. This study is a step for determine the forms of prescription of pain on the balance and muscle strength to build up in future studies a safety of physical exercises for children with sickle cell anemia and improve their functional abilities.

Condition
Sickle Cell Anemia
Tested
Pressure pain tolerance measurement using Digital Pressure Algometer, Balance assessment using HUMAC balance system, Low...
Sponsor
Adly A Adam

Who can join

Age
9 to 14 years
Sex
All sexes
Healthy volunteers
Accepted

Inclusion 9

  • Minimum age: 9 years
  • Maximum age: 14 years
  • Study condition: Sickle Cell Anemia
  • Age range range was 9-14 years old.
  • Could follow given instructions.
  • Children with Sickle cell anemia were medically stable, and take their medications regularly.
  • Children with Sickle cell anemia had experience of chronic pain that lasts more than 6 months.
  • All children with Sickle cell anemia have average weight, height, and body mass index based on their age percentiles.
  • All normal healthy children did not participating in regular sport activities, particularly including lower limb strengthening.

Exclusion 9

  • Defined cardiovascular or respiratory disorders.
  • Renal failure.
  • Myocardial infarction, mainly within last month.
  • Unstable angina.
  • Recent thoracoabdominal surgery.
  • Thoracic or abdominal aneurysm or current pneumothorax.
  • Painful vaso-occlusive crises.
  • Muscular contractures, Joints' stiffness, or deformities.
  • Neuromuscular problems i.e., myositis or peripheral neuropathy.

Where

1 site, 1 recruiting

El-Tahrir st.- in front of Ben El-Sarayat, Ad Doqi Al Giza, Giza Governate

Giza, Egypt

Recruiting

Contact

Potential match only. Final eligibility is determined by the study team.