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Neurodegenerative Diseases Progression Markers (MARKERS-NDD)

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About this study

MARKERS-NDD is a prospective, observational, longitudinal study, which aims to collect data from patients affected by neurodegenerative diseases (NDD) followed longitudinally for routine examinations performed as part of normal clinical practice. Data collected from clinical evaluations, movement analysis, brain imaging, neuropsychological and electroencephalographic assessments, blood chemistry tests will be analysed to carry out statistical investigations and predictive analyses, also using artificial intelligence systems, which allow the identification of new early markers of diagnosis and prognosis of neurodegenerative diseases.

Condition
Neurodegenerative Diseases, Parkinson Disease, Synucleinopathies, Lewy Body Disease, Multiple System Atrophy, Tauopathies, Alzheimer Disease, Corticobasal Degeneration, Supranuclear Palsy, Progressive, Atypical Parkinsonism, TDP-43 Proteinopathies, Amyotrophic Lateral Sclerosis, Frontotemporal Lobar Degeneration, Movement Disorders, Cognitive Impairment, Dementia, Iron Overload, Neurodegeneration With Brain Iron Accumulation (NBIA)
Tested
Observation
Sponsor
Casa di Cura San Raffaele Cassino

Who can join

Age
10 years and older
Sex
All sexes
Healthy volunteers
Not accepted

Inclusion 16

  • Minimum age: 10 years
  • Study condition: Neurodegenerative Diseases, Parkinson Disease, Synucleinopathies, Lewy Body Disease, Multiple System Atrophy, Tauopathies, Alzheimer Disease, Corticobasal Degeneration, Supranuclear Palsy, Progressive, Atypical Parkinsonism, TDP-43 Proteinopathies, Amyotrophic Lateral Sclerosis, Frontotemporal Lobar Degeneration, Movement Disorders, Cognitive Impairment, Dementia, Iron Overload, Neurodegeneration With Brain Iron Accumulation (NBIA)
  • Patients with diagnosis of Parkinson's Disease, Parkinsonism and Movement Disorders
  • Patients with diagnosis of Parkinson's Disease
  • Diagnosis of Parkinson's Disease according to the United Kingdom (UK) Parkinson's Disease Society Brain Bank
  • Diagnosis of Movement Disorder not related to Parkinson's Disease
  • Diagnosis of Multiple System Atrophy (MSA) in accordance with Second Consensus Statement on Diagnosis of Multiple System Atrophy;
  • Diagnosis of Progressive Supranuclear Palsy according to Movement Disorder Society for Diagnosis of Progressive Supranuclear Palsy;
  • Diagnosis of Essential Tremor
  • Willing to participate in the study, understand the procedures and sign the informed consent.
  • Patients affected by cognitive impairment (CI) and dementia
  • Diagnosis of probable:
  • Lewy Body Dementia
  • Alzheimer's Disease
  • Mild Cognitive Decline
  • Subjective memory complaints

Exclusion 1

  • There are no restrictions for participation in the study based on age, severity of illness or presence of cognitive impairment, as long as the person is able to complete the research assessments.

Where

1 site, 1 recruiting

San Raffaele Cassino

Cassino, Frosinone, Italy

Recruiting

Contact

Potential match only. Final eligibility is determined by the study team.