Transcranial Pulse Stimulation. a Potential Treatment for Early Dementia
About this study
Alzheimer's Disease (AD) is characterized by the absence of treatments to slow, stop, or reverse its course, with patients finally losing cognitive functions, skills and independence. It is a chronic degenerative disease with high social and medical burden worldwide: AD ranked third among neurological disorders in terms of disability-adjusted life years (DALY) rates. The primary aim of the research protocol is to improve care for patients with AD, by implementing, with an innovative method, the currently available repertoire of neuromodulation techniques. For this aim, we will investigate whether Transcranial Pulse Stimulation (TPS) may induce cognitive improvement in patients with an early stage of dementia.
- Condition
- Alzheimer Disease
- Tested
- Transcranial Pulse Stimulation
- Sponsor
- Francesca Pistoia
Who can join
- Age
- 18 years and older
- Sex
- All sexes
- Healthy volunteers
- Not accepted
Inclusion 6
- Minimum age: 18 years
- Study condition: Alzheimer Disease
- age\>18 years
- diagnosis of early dementia according to current international guidelines
- disease duration of at least 12 months
- consent to participate in the study.
Exclusion 4
- medical instability interfering with standard neurological assessment
- any contraindication to preliminary MRI for MR-based real-time neuronavigation
- comorbidities which may interfere with cognitive status
- any contraindication to Transcranial Pulse Stimulation.
Where
2 sites, 2 recruiting
San Salvatore Hospital
L’Aquila, Italy, Italy
San Salvatore Hospital
L’Aquila, Italy, Italy
Contact
-
Francesca Pistoia, MD, PhD
+39862368657 francesca.pistoia@univaq.it
Potential match only. Final eligibility is determined by the study team.