A Study on Treatment for Patients With BRAFV600E Mutant Metastatic Colorectal Cancer (mCRC)
About this study
Previous studies have shown that BRAFV600E mutant mCRC patients have a shorter survival time than BRAF wild type mCRC patients. For Chinese patients, however, it remains unclear about the BRAF gene mutation rate, diagnosis, prognosis and survival data in people with BRAFV600E mutant mCRC . This real-world, multicenter non-interventional study (NIS) will describe the mutation rate, treatment patterns, effectiveness and safety of current treatment regimens in BRAFV600E mutant mCRC patients in China.
- Condition
- Metastatic Colorectal Cancer, BRAF V600 Mutation
- Tested
- Non interventional study
- Sponsor
- Fudan University
Who can join
- Age
- 18 years and older
- Sex
- All sexes
- Healthy volunteers
- Not stated
Inclusion 4
- Minimum age: 18 years
- Study condition: Metastatic Colorectal Cancer, BRAF V600 Mutation
- Diagnosis of histologically or cytologically confirmed CRC that is metastatic and unresectable
- Presence of BRAFV600E mutation in tumor tissue, as confirmed by a local assay
Exclusion 1
- patients with previous chronic inflammatory bowel disease, chronic diarrhea or recurrent bowel obstruction patients with symptomatic brain metastases active clinical severe infection
Where
1 site, 1 recruiting
Fudan University Shanghai Cancer Center
Shanghai, Shanghai Municipality, China
Potential match only. Final eligibility is determined by the study team.