Advancing Feasibility and Acceptability of Digital Cognitive Rehabilitation in Sickle Cell Disease
About this study
This is a single site nonrandomized pilot clinical trial of the feasibility, acceptability, and efficacy of a combination treatment involving digital Cogmed working memory skills training, social support components, and memory strategy training to improve adherence to Cogmed in youth with sickle cell disease ages 7-16 years.
- Condition
- Sickle Cell Disease
- Tested
- Cogmed+
- Sponsor
- Children's National Research Institute
Who can join
- Age
- 7 to 16 years
- Sex
- All sexes
- Healthy volunteers
- Not accepted
Inclusion 6
- Minimum age: 7 years
- Maximum age: 16 years
- Study condition: Sickle Cell Disease
- Diagnosis of sickle cell disease (any genotype).
- Between ages 7-16 years old.
- Patients will only enter the treatment phase if they score \>1 SD below the normative mean on at least one standardized working memory assessment (i.e., Digit Span or Spatial Span subtests) or demonstrate a relative weakness in working memory (\>1 SD below the estimated IQ).
Exclusion 5
- Motor, visual, or auditory impairment that prevents computer use.
- Diagnosis of a mental health condition that precludes, or takes treatment precedence over, participation in the cognitive training.
- History of photosensitive seizures.
- Insufficient English fluency.
- Recent initiation or dose adjustment of a stimulant medication to treat attention problems (\< 30 days).
Where
1 site, 1 recruiting
Children's National Hospital
Washington D.C., District of Columbia, United States
Contact
-
Steven Hardy, PhD
202-476-5000 sjhardy@childrensnational.org
-
Sara Ropeta, BS
202-476-5000 sropeta@childrensnational.org
Potential match only. Final eligibility is determined by the study team.