WISE-2B Brain Study (Weight Loss Intervention Surgical Effects on Brain Function)
About this study
The goal of the study to understand the effects of weight loss and improvements in diabetes following bariatric surgery on brain function and thinking. This study will also examine whether non-invasive transcutaneous vagal nerve stimulation (tVNS) intervention initiated 30 days post-surgery improves brain function and thinking. The study does NOT cover any costs associated with bariatric surgery.
- Condition
- Diabetes, Weight Loss
- Tested
- tVNS, Complete Vagotomy, Anterior Vagotomy
- Sponsor
- University of Florida
Who can join
- Age
- 20 to 75 years
- Sex
- All sexes
- Healthy volunteers
- Accepted
Inclusion 8
- Minimum age: 20 years
- Maximum age: 75 years
- Study condition: Diabetes, Weight Loss
- Between age: 20-75 yrs, English speaking, Physically mobile
- Body Mass Index (BMI) \>35 kg before surgery
- Compatible of MRI Scanning
- Willing to give a small blood sample
- Capable of providing informed consent
Exclusion 4
- Prior or current neurological disorder
- Major psychiatric disturbance
- Unstable medical conditions (cancer)
- MRI contraindications (claustrophobia, metal implants, waist/torso circumference)
Where
1 site, 1 recruiting
University of Florida - College of Public Health and Health Professions
Gainesville, Florida, United States
Contact
-
Keyanni J Johnson
3522945618 kjjohnson@ufl.edu
-
Ronald Cohen, PhD
352-295-5840 roncohen@ufl.edu
Potential match only. Final eligibility is determined by the study team.