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Recruiting

Pre-malignant States to Hematologic Malignancies in Firefighters

About this study

The purpose of the study is to evaluate if firefighter exposure to hazardous compounds will increase the incidence of premalignant hematological states which subsequently increases the risk of the development of hematologic malignancies, and potentially other pathophysiological consequences.

Condition
Clonal Hematopoiesis of Indeterminate Potential, Monoclonal Gammopathy, Non Hodgkin Lymphoma, Leukemia, Multiple Myeloma, Plasma Cell Disorder
Tested
Monoclonal Gammopathy, Complete Blood Count with differential (CBC w/ diff), Clonal hematopoiesis (CHIP)
Sponsor
Wake Forest University Health Sciences

Who can join

Age
40 to 49 years
Sex
All sexes
Healthy volunteers
Accepted

Inclusion 7

  • Minimum age: 40 years
  • Maximum age: 49 years
  • Study condition: Clonal Hematopoiesis of Indeterminate Potential, Monoclonal Gammopathy, Non Hodgkin Lymphoma, Leukemia, Multiple Myeloma, Plasma Cell Disorder
  • Written informed consent and HIPAA authorization for release of personal health information.
  • Age ≥ 40-49 years at the time of consent (self-reported)
  • Ability of the participant to understand and comply with study procedures for the entire length of the study
  • Currently employed by Charlotte Fire Department (CFD) with at least 5 years on-the -job experience (self-reported)

Exclusion 1

  • Anyone with a current diagnosis of a hematologic malignancy will be excluded.

Where

1 site, 1 recruiting

Levine Cancer Institute

Charlotte, North Carolina, United States

Recruiting

Contact

Potential match only. Final eligibility is determined by the study team.