Delivering Patient-Facing Evidence-Based Guidelines Through mHealth to Adults With Sickle Cell Disease
About this study
In a hybrid type I effectiveness-implementation trial, our three-center research teams aim to examine whether empowering adults with sickle cell disease (SCD) with patient-facing SCD-specific guidelines through an mHealth application with booklets will decrease acute healthcare utilization and be cost-effective over booklets with the guidelines alone. Our team, head will test our hypotheses with the following aims: Aim 1: evaluate the effectiveness of the patient-facing guidelines mHealth app + booklet intervention to decrease acute healthcare utilization (hospitalizations, emergency room visits, and day hospital visits) in adults with SCD over the standard care in a randomized controlled trial, Aim 2: evaluate the implementation outcomes of the mHealth app + booklet using the capability, opportunity, and motivation-behavior (COM-B) and reach, effectiveness, adoption, implementation, and maintenance (RE-AIM) frameworks, and Aim 3: evaluate the cost-effectiveness of patient-facing mHealth app + booklets vs. standard care in adults with SCD. is hybrid effectiveness-implementation trial design, according to the COM-B and RE-AIM frameworks with a mixed-methods approach, will give valuable insights into the effects, facilitators, and barriers to the implementation that will influence the effects of the patient-facing guidelines intervention.
- Condition
- Sickle Cell Disease
- Tested
- mHealth app + booklets
- Sponsor
- Ohio State University
Who can join
- Age
- 18 years and older
- Sex
- All sexes
- Healthy volunteers
- Not accepted
Inclusion 7
- Minimum age: 18 years
- Study condition: Sickle Cell Disease
- receiving care at the SCD clinic for the prior 12 months,
- has a diagnosis of SCD (Hgb SS, SC, Sβ-thal),
- able to speak and understand written English,
- older than 18 years.
- (1) to be involved in participants' clinical care
Where
4 sites, 4 recruiting
University of Illinois at Chicago
Chicago, Illinois, United States
The Ohio State University Medical Center
Columbus, Ohio, United States
Vanderbilt University
Nashville, Tennessee, United States
Washington University St. Louis
St Louis, Missouri, United States
Contact
-
Robert M Cronin, MD, MS
6146889220 robert.cronin@osumc.edu
Potential match only. Final eligibility is determined by the study team.