Recruiting Phase 3

Improving Functional Outcomes and Quality of Life in Patients With Rectal Cancer After Surgery With Intensified Follow-up & Surveillance

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About this study

The goal of this clinical study is to gain further insights into the treatment of patients with Low Anterior Resection Syndrome (LARS) symptoms after rectal resection. The main question is: Can LARS symptoms and quality of life be improved by implementing an intensified follow-up program? Researchers will compare the results of the intervention group with the results of a control group in which patients do not receive an intensified follow-up program to determine whether the intervention works. Participants will undergo an intensified follow-up program which consists of several follow-up visits and medical treatment, pelvic floor muscle training and gynaecological and urological co-treatment in case of LARS symptoms and urinary or sexual complaints.

Condition: LARS - Low Anterior Resection Syndrome, Rectal Cancer Surgery, Rectal Cancer, Quality of Life (QOL)
Tested: Intensified follow-up program
Sponsor: University Hospital, Basel, Switzerland

Who can join

Age: 18 years and older
Sex: All sexes
Healthy volunteers: Not accepted

Inclusion 5

Minimum age: 18 years
Study condition: LARS - Low Anterior Resection Syndrome, Rectal Cancer Surgery, Rectal Cancer, Quality of Life (QOL)
patients older than 18 years
patients with rectal cancer in the middle and lower third of the rectum in stages I to IV who underwent LAR with TME and protective ileostomy
able to give informed consent as documented by signature

Exclusion 2

dementia or other psychiatric disorder that would prevent the patients from answering the questionnaires and experiencing sustainable training effects
impossibility of stoma reversal due to persistent anastomotic leak and/or local recurrence

Where

5 sites, 5 recruiting

Clarunis Universitäres Bauchzentrum Basel

Basel, Switzerland

Recruiting

Lindenhofspital Bern

Bern, Switzerland

Recruiting

Kantonsspital Luzern

Lucerne, Switzerland

Recruiting

Kantonsspital Winterthur

Winterthur, Switzerland

Recruiting

St. Anna Spital Bern

Bern, Switzerland

Recruiting

Contact

Felicitas Wiedemann, Resident

+41 61 777 76 09 felicitasinga.wiedemann@clarunis.ch
Marco von Strauss und Torney, Senior physician

+41 61 777 7581 marco.vonstrauss@clarunis.ch

Potential match only. Final eligibility is determined by the study team.