Randomized Controlled Trial of the Effects of Combined Resistance and AerobiC Exercise on Health-related Quality of Life in Patients Undergoing First-line Chemotherapy for Metastatic Colorectal Cancer (REACH)
About this study
The primary objective of this trial is to compare the effects of 18 weeks structured exercise training versus on control on healt-related quality of life in patients with mCRC undergoing first-line chemotherapy.
- Condition
- Metastatic Colorectal Cancer (mCRC)
- Tested
- Exercise training
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Who can join
- Age
- 18 years and older
- Sex
- All sexes
- Healthy volunteers
- Not accepted
Inclusion 3
- Minimum age: 18 years
- Study condition: Metastatic Colorectal Cancer (mCRC)
- \- Adults (≥18 years of age) schduled to undergo first-line chemotherapy for the treatment of metastatic colorectal cancer.
Exclusion 6
- Pregnancy.
- A life expectancy of \< 6 months.
- Absolute contraindications to maximal exercise, as per the recommendations by the Danish Society of Cardiology.
- ECOG (Eastern Cooperative Oncology Group) performance status \> 2.
- Inability to understand the Danish or English language.
- Engagement in structured moderate-to-high aerobic exercise training for \>30 min \>1 times/week for the past 3 months at the time of inclusion.
Where
4 sites, 4 recruiting
Centre for Physical Activity Research, Copenhagen Univerisity Hospital - Rigshospitalet
Copenhagen, Denmark
Herlev and Gentofte Hospital
Herlev, Denmark
North Zealand University Hospital, Hillerød
Hillerød, Denmark
Zealand University Hospital, Roskilde
Roskilde, Denmark
Contact
-
Casper Simonsen, Phd
+45 35 45 76 41 casper.simonsen@regionh.dk
Potential match only. Final eligibility is determined by the study team.