Exercise Therapy and Cognitive Behavioural Therapy for Fatigue in Female Cancer Patients in Singapore
About this study
The purpose of this research study is to investigate the acceptability, feasibility, and effectiveness of exercise therapy and cognitive behavioral therapy (CBT) in improving fatigue levels and breast cancer treatment adherence in breast cancer patients.
- Condition
- Fatigue, Breast Cancer Female
- Tested
- Graded Exercise Therapy Arm (GET), Experimental: Exercise Therapy (GET) plus Cognitive Behavioural Therapy (CBT)
- Sponsor
- National Cancer Centre, Singapore
Who can join
- Age
- 21 years and older
- Sex
- Female only
- Healthy volunteers
- Not accepted
Inclusion 15
- Minimum age: 21 years
- Eligible sex: Female
- Study condition: Fatigue, Breast Cancer Female
- Primary cohort (N=90):
- Female
- ≥21 years of age
- Stage I-III breast cancer regardless of hormone receptor status or human epidermal growth factor receptor 2 (HER2) status
- Completed surgery
- Completed adjuvant chemotherapy, if indicated
- Reported fatigue (One-item fatigue scale score ≥ 4)
- Ability to read and communicate in English
- Willing to provide informed consent for the study participation
- Exploratory cohort (N=10):
- Stage IV breast cancer regardless of hormone receptor status or human epidermal growth factor receptor 2 (HER2) status
- Currently receiving systemic therapy (e.g. endocrine therapy, chemotherapy, targeted therapy or immunotherapy)
Exclusion 10
- Pregnant or lactating
- Presence of dementia or major psychiatric disease
- Deemed medically unsuitable by medical team for low to moderate intensity exercise
- Unable or unwilling for tele-counselling sessions
- Uncontrolled pain or undiagnosed pain
- Low blood counts: Hb \<8.0, Platelet \<50K, ANC \<1
- Electrolyte imbalances: K \<3.0, Na \<130
- Cardiovascular diseases, including but not limited to: LVEF \<35%, uncontrolled arrhythmias, severe coronary artery disease, severe valvular heart disease, uncontrolled hypertension etc. not cleared by a cardiologist
- Active infection
- Currently engaged in moderate to vigorous physical activity
Where
4 sites, 4 recruiting
National Cancer Centre, Singapore (NCCS)
Singapore, Singapore
Singapore General Hospital
Singapore, Singapore
NCCS Satellite Clinic @ Changi General Hospital
Singapore, Singapore
NCCS Satellite Clinic @ Sengkang General Hospital
Singapore, Singapore
Contact
-
Dr Ryan Shea YC TAN, MBBS, MRCP(UK), MMed
+65 63065771 ryan.shea.tan.y.c@singhealth.com.sg
-
Michelle Chow
Potential match only. Final eligibility is determined by the study team.