Recruiting
Memory Deterioration in Alzheimer Disease
About this study
Semantic AD
- Condition
- Alzheimer Disease, Neurodegenerative Diseases, Magnetic Resonance Imaging, Memory Impairment
- Tested
- 7T MRI, EEG, Blood samples, Stool samples, Neuropsychologic test (MoCA)
- Sponsor
- Norwegian University of Science and Technology
Who can join
- Age
- 55 years and older
- Sex
- All sexes
- Healthy volunteers
- Accepted
Inclusion 6
- Minimum age: 55 years
- Study condition: Alzheimer Disease, Neurodegenerative Diseases, Magnetic Resonance Imaging, Memory Impairment
- Confirmed diagnosis based on current ICD criteria for AD or MCI .
- \>55years.
- Norwegian native speaker
- Lives at home and not in a health institution
Exclusion 10
- Patients with severe cognitive impairment that prevents assessment with the selected modalities (planned cut-off: CDR \> 2).
- Presence of brain tumors.
- History of traumatic brain injury.
- History of cranial surgery.
- Contraindications to the selected imaging modalities (e.g., 7T MRI or EEG).
- Diagnosis of other neurodegenerative diseases such as Parkinson's disease or ALS.
- T MRI contraindications:
- Large tattoos close to the head region, permanent makeup or unremoveable piercings
- Certain models of pacemakers (if pacemaker implantet, MRI physicist at 7T-lab will be conferred)
- Implantet metal in body (clips, stents, prothesis, skrews, plates, teeth etc.)
Where
1 site, 1 recruiting
Norwegian University of Sciene and Technology / Norges teknisk-naturvitenskapelige universitet (NTNU)
Trondheim, Trønderlag, Norway
Contact
-
Axel Sandvig Professor, MD & PhD
+4745840578 axel.sandvig@ntnu.no
-
Varanann Varathalingam
Potential match only. Final eligibility is determined by the study team.