DEXDES Trial: Dexmedetomidine-Desflurane Combination in Laparoscopic Colectomy
About this study
This randomized double-blind controlled clinical trial aims to evaluate the efficacy and safety of combining Dexmedetomidine with Desflurane in patients undergoing elective laparoscopic colectomy. The study will assess whether the combination can reduce Desflurane consumption, improve intraoperative hemodynamic stability, and enhance postoperative recovery compared to Desflurane alone.
- Condition
- Colorectal Neoplasms
- Tested
- Dexmedetomidine + Desflurane, Desflurane + Normal Saline
- Sponsor
- Tam Anh Research Institute
Who can join
- Age
- 18 to 65 years
- Sex
- All sexes
- Healthy volunteers
- Not accepted
Inclusion 7
- Minimum age: 18 years
- Maximum age: 65 years
- Study condition: Colorectal Neoplasms
- Age 18-65 years
- ASA Physical Status I-II
- Elective laparoscopic colectomy
- Written informed consent provided
Exclusion 5
- Severe cardiac, hepatic, or renal disease
- COPD or bronchial asthma
- Chronic opioid or psychotropic medication use
- Atrioventricular block (grade II-III), sick sinus syndrome
- Significant intraoperative bleeding or hemodynamic instability
Where
1 site, 1 recruiting
Tam Anh TP. Ho Chi Minh General Hospital
Ho Chi Minh City, Ho Chi Minh, Vietnam
Contact
-
Phan Quoc Thai, MD
+84 964 152 360 thaipq@tahospital.vn
Potential match only. Final eligibility is determined by the study team.