Predictors of Emergency Department Use in Frail Patients
About this study
When admitted to the emergency department (ED), elderly non-autonomous patients show high risk of adverse health outcomes. The prompt identification of ED use risk factors in such population is hence needed. While cognitive impairment is a known clinical risk factor, biomarkers of most prevalent dementias have been scarcely investigated as possible ED use predictors. Within this context, this prospective study aims at exploring whether plasma phospho-tau181 and cerebrovascular burden can predict ED use at 6 months in elderly non-autonomous patients, irrespective of frailty.
- Condition
- Alzheimer s Disease, Vascular Dementia, Frailty, Elderly, Emergency Department Visits, Autonomy
- Tested
- Plasma phosphorylated Tau 181
- Sponsor
- University of Pisa
Who can join
- Age
- 65 years and older
- Sex
- All sexes
- Healthy volunteers
- Not accepted
Inclusion 7
- Minimum age: 65 years
- Study condition: Alzheimer s Disease, Vascular Dementia, Frailty, Elderly, Emergency Department Visits, Autonomy
- fluency in Italian language,
- age higher than 64 years,
- loss of autonomies of daily living as assessed by the Katz Activities of Daily Living or in the Lawton Instrumental Activities of Daily Living questionnaires,
- having performed routinary blood exams in the 6 months prior to recruitment
- having performed head neuroimaging feasable for cerebrovascular burden assessment, i.e., Magnetic Resonance Imaging (MRI) or computed tomography (CT), in the 6 months prior to recruitment.
Exclusion 1
- withdrawal of the informed consent
Where
1 site, 1 recruiting
Azienda Ospedaliera Universitaria Pisana
Pisa, Pisa, Italy
Contact
-
Francesco Turco, MD, PhD
+39-050992905 francesco.turco@phd.unipi.it
Potential match only. Final eligibility is determined by the study team.