Efficacy of CAD in Screening Colonoscopy to Reduce the Risk of Advanced Adenoma at 3 Years.
About this study
The occurrence of interval cancers after colonoscopy raises the possibility of missed lesions. High- performance computer aided diagnosis (CAD) systems have been specially designed for the detection of colorectal lesions (CAD for detection is named CADe). The use of CADe improves adenoma detection in screening colonoscopy. The potential of CADe system in reducing the rate of progression to advanced polyps or interval cancer between two colonoscopies remains still uncertain.
- Condition
- Colonoscopy, Colorectal Neoplasms, Intestinal Polyps
- Tested
- Standard colonoscopy, Colonoscopy CADe
- Sponsor
- University Hospital, Bordeaux
Who can join
- Age
- 18 years and older
- Sex
- All sexes
- Healthy volunteers
- Not accepted
Inclusion 5
- Minimum age: 18 years
- Study condition: Colonoscopy, Colorectal Neoplasms, Intestinal Polyps
- Patients over 18 years of age with indication for colonoscopy as part of a screening program, after a positive immunological (FIT) test, and/or for personal or family history of colorectal cancer and/or personal history of colonic adenomas and/or sessile serrated polyp,
- Written informed consent signed
- Patients covered by a health-care insurance.
Exclusion 9
- Failed complete colonoscopy, defined by the absence of cecal intubation or identification of the terminal ileum.
- Inadequate bowel preparation (Boston bowel preparation score \< 6, and/or least at one part of colon with score ≤ 1)
- An infiltrative tumor was diagnosed during colonoscope insertion time, not accessible to endoscopic resection and likely to require surgical management (a procedure where part of the colon may need to be removed).
- Patient under guardianship or protection
- Pregnant women
- Not fluent in French or illiterate
- Personal history of inflammatory bowel disease
- Personal history of genetic predisposition of CRC
- Personal history of major colorectal surgery involving total or subtotal colectomy
Where
15 sites, 15 recruiting
CHU Bordeaux - Hôpital Haut Lévêque
Pessac, France
CH de la Côte Basque
Bayonne, France
CHU Brest la Cavale Blanche
Brest, France
Hôpital de Carhaix
Carhaix-Plouguer, France
Clinique Paris Bercy
Charenton-le-Pont, France
CHU de Limoges
Limoges, France
and 9 more sites on ClinicalTrials.gov
Contact
-
Arthur BERGER, MD
+335 57 67 49 31 arthur.berger@chu-bordeaux.fr
Potential match only. Final eligibility is determined by the study team.