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Deep Learning on Amyloid Positons Emission Tomography

About this study

Reducing injected dose and/or acquisition time in amyloid PET imaging would improve comfort, radiation safety and cost-effectiveness in diagnosis and follow-up of patients. This study evaluates the impact of a deep learning-based noise reduction algorithm on visual analysis and Centiloid quantification when simulating reduced injected doses of \[18F\]flutemetamol.

Condition
Alzheimer Disease
Sponsor
Central Hospital, Nancy, France

Who can join

Age
18 to 99 years
Sex
All sexes
Healthy volunteers
Not stated

Inclusion 5

  • Minimum age: 18 years
  • Maximum age: 99 years
  • Study condition: Alzheimer Disease
  • Patients with objective cognitive impairment,
  • Referred to our department for a cerebral \[¹⁸F\]flutemetamol positron emission tomography scan between January 1, 2023 and July 1, 2025,

Exclusion 1

  • Patient have objected to the use of their data.

Where

3 sites, 3 recruiting

CHRU NANCY Brabois, nuclear medicine department

Vandœuvre-lès-Nancy, France

Recruiting

Nancy's hospital

Vandœuvre-lès-Nancy, France

Recruiting

Nuclear medicine department CHRU de NANCY Brabois

Vandœuvre-lès-Nancy, France

Recruiting

Contact

Potential match only. Final eligibility is determined by the study team.