Endoscopic Nipple-Sparing Mastectomy Through a Single Axillary Incision in Breast Cancer
About this study
This single-center prospective study will evaluate the feasibility and safety of endoscopic nipple-sparing mastectomy (E-NSM) performed through a single axillary incision in selected women with breast cancer undergoing direct-to-implant breast reconstruction. The study will assess procedural feasibility, completeness of resection, short-term postoperative complications, and patient-reported outcomes
- Condition
- Breast Cancer - Ductal Carcinoma in Situ (DCIS), Breast Cancer
- Tested
- Endoscopic Nipple-Sparing Mastectomy (E-NSM)
- Sponsor
- Fondazione del Piemonte per l'Oncologia
Who can join
- Age
- 18 years and older
- Sex
- Female only
- Healthy volunteers
- Not accepted
Inclusion 8
- Minimum age: 18 years
- Eligible sex: Female
- Study condition: Breast Cancer - Ductal Carcinoma in Situ (DCIS), Breast Cancer
- Female participants aged 18 years or older.
- Diagnosis of early-stage invasive breast cancer or ductal carcinoma in situ, including multifocal or multicentric disease.
- Candidate for nipple-sparing mastectomy with immediate direct-to-implant reconstruction.
- Small- to medium-sized breasts with ptosis grade 2 or less.
- Written informed consent provided.
Exclusion 6
- Preoperative evidence of skin involvement, nipple-areola complex involvement, lymph-node metastases, inflammatory breast cancer, Paget's disease, mesenchymal breast tumors, or recurrent breast cancer.
- Previous ipsilateral breast surgery.
- Previous thoracic radiation therapy.
- Heavy smoking (\>20 cigarettes/day), uncontrolled diabetes mellitus, or body mass index \>30.
- ASA score 3 or higher.
- Ongoing pregnancy
Where
1 site, 1 recruiting
Breast Unit
Candiolo, Turin, Italy
Contact
-
Antonio Toesca, MD
0119933628 antonio.toesca@ircc.it
-
Giada Pozzi, MD
0119933676 giada.pozzi@ircc.it
Potential match only. Final eligibility is determined by the study team.