Opportunistic Breast Cancer Screening Using Non-Contrast Chest CT
About this study
The goal of this observational study is to evaluate the feasibility and effectiveness of using non-contrast chest computed tomography scans for opportunistic breast cancer screening, and to further compare its diagnostic performance with conventional imaging modalities, including mammography and/or breast magnetic resonance imaging.
- Condition
- Breast Cancer
- Sponsor
- Fudan University
Who can join
- Age
- 18 years and older
- Sex
- Female only
- Healthy volunteers
- Accepted
Inclusion 8
- Minimum age: 18 years
- Eligible sex: Female
- Study condition: Breast Cancer
- Female patients who have undergone non-contrast chest CT examination;
- Participants included in the comparative analysis must have undergone at least one comparator imaging modality (mammography and/or breast MRI);
- If a breast lesion is detected, it must be confirmed by pathology or clinical follow-up at least 12 months;
- No prior systemic or local therapy before imaging examinations;
- Imaging data are complete and of sufficient quality for analysis.
Exclusion 5
- History of other malignancies with potential impact on breast imaging interpretation;
- Participants with suspected malignant breast lesions but no confirmation;
- Prior radiotherapy, chemotherapy, or immunotherapy before imaging examinations;
- Imaging data that are incomplete, of poor quality, or contain significant artifacts preventing reliable analysis;
- Time interval between non-contrast chest CT and comparator imaging modalities exceeding three months, or with clinical events occurring between examinations that may alter lesion status.
Where
1 site, 1 recruiting
Fudan University Shanghai Cancer Center
Shanghai, China
Contact
-
Chao You, MD
+86-021-15800780035 youchao@fudan.edu.cn
-
Yajia Gu, MD
+86-021-18017312040 guyajia@fudan.edu.cn
Potential match only. Final eligibility is determined by the study team.