Alcohol, Breast Cancer, and Metabolism
About this study
Alcohol consumption, even at low levels, has been associated with increased breast cancer risk, but the biological mechanisms underlying this relationship remain unclear. This study will examine whether breast tissue may locally metabolize alcohol by measuring alcohol-related compounds in paired blood and breast milk samples from lactating women. The findings may help clarify alcohol-related biological pathways relevant to breast cancer risk and improve risk communication.
- Condition
- Alcohol Drinking, Ethanol Intoxication, Breastfeeding
- Tested
- Low-alcohol level exposure, Breast-pumping time
- Sponsor
- University of Illinois at Urbana-Champaign
Who can join
- Age
- 21 to 45 years
- Sex
- Female only
- Healthy volunteers
- Accepted
Inclusion 9
- Minimum age: 21 years
- Maximum age: 45 years
- Eligible sex: Female
- Study condition: Alcohol Drinking, Ethanol Intoxication, Breastfeeding
- All aims
- Drink alcohol (at least one alcoholic drink during lactation of a lactating female)
- For aims 1 and 2
- Nursing a 2- to 5-month-old infant
- Experienced with a breast pump
Exclusion 9
- Pregnant
- Lifetime history of alcohol dependence
- Drink more than 3 standard drinks per day or more than 7 standard drinks per week in the month previous to enrollment
- Current regular use of drugs with addiction potential (other than alcohol)
- Use of medications known to interact with alcohol metabolism
- Current smoking
- Anemia
- Diabetes
- Liver disease
Where
1 site, 1 recruiting
Bevier Hall; University of Illinois at Urbana Champaign
Urbana, Illinois, United States
Contact
-
Marta Y Pepino de Gruev, Ph D
217-300-2374 ypepino@illinois.edu
Potential match only. Final eligibility is determined by the study team.